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Skip Navigation LinksHome   >   Investors   >   Business Model & Strategy

Business Model & Strategy

Business Model

OCT is a pharmaceutical company focused on the development of cannabinoid-based prescription medicines to target indications in the £42.5bn pain market, with regulatory marketing approval from agencies including the FDA1, EMA2 and MHRA3.

We have pursued a partnering model since it was established, with its highly experienced management team working closely with a range of carefully selected external academic and commercial partners. This includes an umbrella research collaboration agreement that was signed with the University of Oxford when OCT launched, and is continually evolving, with new partners engaged across the value chain to drive further research and development activities.

Strategy

OCT aims to become a global leader in developing prescription medicines that target the endocannabinoid system and address significant unmet medical needs.

To achieve our aim, we use a drug development strategy that includes three inputs, in order to create a drug portfolio that balances risk, value and time to market, whilst ensuring market exclusivity around all of its key activities:

  • Unmodified natural compounds derived from cannabis (pCBs) and other cannabis-based compounds, targeting orphan indications.
  • Cannabinoid derivatives, which are pCBs that have been chemically modified through medicinal chemistry to improve physicochemical properties and drug-like characteristics.
  • Synthetic cannabinoids, or cannabinoid memetics, which are compounds that target cannabinoid receptors but are structurally distinct from pCBs. 

We have developed a proprietary library of 93 cannabinoid derivatives, which provides a source for further drug candidates to enter our pipeline. The library of compounds is screened by academic or commercial partners in disease model assays. The chemical modification of the cannabinoid creates a new compound with the potential for protection under composition of matter patents that we believe can be used by the Group to target common indications in addition to rare diseases.

Due to the highly patentable nature of OCT’s derivative compounds, we believe that a wide range of pain-related indications can be targeted by the Group. However, by employing an orphan indication strategy, OCT can also utilise unmodified pCBs and other off-patent compounds to target a group of rare diseases that would not otherwise be approached, and where exclusivity can be obtained. This provides the Group with a faster, less expensive path to commercialisation. Regulatory exclusivity is also granted to companies who develop drugs for these diseases. This market exclusivity allows natural unmodified pCBs to be developed as drug products for rare diseases.

We also intend to capitalise on a collaboration with a top-tier CRO to access a large and diverse chemical library (circa 400,000 compounds) and initiate a development programme aiming to identify a novel cannabinoid mimetic drug candidate targeting the ECS via an undisclosed receptor. This target has the potential to deliver therapeutic intervention in several neuropathic disorders, and also in other neurological, immune-inflammatory and oncology conditions. 

We may also in-licence any of the three types of compounds set out above. In-licensing drug candidates that have passed one or more stages in development provides the Group with an opportunity to advance its drug pipeline more quickly. In-licensing can also be used to diversify a drug pipeline and to target both large and orphan indications.

Company Information

OCT is incorporated under the laws of England and Wales under the Companies Act 2006 and the company number 13179529. The Company’s main country of operations is the United Kingdom, where it is headquartered.

1. Food and Drug Administration
2. European Medicines Agency
3. Medicines and Healthcare products Regulatory Agency